LOUISVILLE, Ky. 鈥 More than a dozen internationally recognized scientists from across North America and Great Britain working at the forefront of cell and molecular biology of development and disease are scheduled to speak in Louisville at the , May 15-16, 2019. The two-day program will cover the most recent directions and conceptual advances in spinal cord injury research.
Ian Wickersham, Ph.D., of the will deliver the keynote presentation on re-engineering the rabies virus. In his Ph.D. work, Wickersham and his colleagues introduced the use of recombinant rabies virus as a tool for neuroscience and originated the paradigm of monosynaptic tracing, meaning the use of a genetically modified viral vector to identify neurons directly connected to a targeted neuronal population. joined MIT in 2007 and started the Genetic Neuroengineering Group there in 2013.
Extensive time for poster sessions will allow participating trainees to highlight their research and foster new collaborations among senior scientific colleagues.
The symposium is sponsored by the Kentucky Spinal Cord and Head Injury Research Trust, The Craig H. Neilsen Foundation, The and the . The annual event is hosted in alternating years by UofL and the University of Kentucky. The 2019 event will be held at the Louisville Downtown Embassy Suites Hotel.
Symposium registration fees, including breakfast, lunch and reception for all attendees:
- Professional or Faculty: $275
- Postdocs, Residents, Staff, Community Members: $155
- Students: $90
To register:听
Rooms are available at the Louisville Downtown Embassy Suites for the special symposium rate of $159/night plus tax. Room reservations may be made by calling 1鈥502鈥813鈥3800 and referencing the 25th KSCHIRT Symposium. The deadline for hotel reservations at the symposium rate is April 16.
Preliminary program:
Wednesday, May 15, 2019
Opening Remarks – Scott R. Whittemore, Ph.D., Director, Kentucky Spinal Cord Injury Research Center, University of Louisville
Introduction of Keynote Speaker – Brandon Brown, M.S., UofL
鈥淩e-engineering rabies virus鈥 – Ian Wickersham, Ph.D. – Massachusetts Institute of Technology
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Session One: Big Data Approaches to Big Questions
Chair: Beatrice Ugiliweneza, Ph.D., UofL
鈥淚ntegrating mechanistic molecular insight with large-scale genomics:听 Path toward personalized therapeutics鈥 – Wolfgang Sadee, Dr.rer.nat. – The Ohio State University
鈥淎ccelerating听reproducibility and clinical听translation through data science: A brief听history of听data sharing, machine learning and discovery in neurotrauma鈥 – Adam Ferguson, Ph.D. – University of California, San Francisco
Session Two: Novel Approaches For Investigating Bladder And Bowel Dysfunction
Chairs: Charles Hubscher, Ph.D., April Herrity, DC, Ph.D. and Teresa Pitts, Ph.D.
鈥淣eurogenic bowel at the enteric-smooth muscle interface鈥 – Gregory Holmes, Ph.D. – Penn State University
鈥淥pportunities for closed-loop neuromodulation to improve bladder control鈥 – Dennis Bourbeau, Ph.D. – Case Western Reserve University and Louis Stokes Cleveland VA Medical Center
Session Three: Mechanisms of Systemic Disease In Neuroscience
Chairs: Michal Hetman, M.D., Ph.D. and Sujata Saraswat Ohri, Ph.D.
鈥淪pinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex鈥 – Jan Schwab. M.D., Ph.D. – The Ohio State University
鈥淢odulating the mitochondrial electron transport chain protects against trauma-induced neurodegeneration: What can a worm teach us about brain injury?鈥 – Peter Douglas, Ph.D. – University of Texas Southwestern Medical Center
鈥淐ircadian influences on neurodegeneration鈥 – Eric Musiek, M.D., Ph.D. – Washington University School of Medicine
Session Four: From Motor Units To Rehabilitation
Chairs: David Rouffet, Ph.D. and Jessica D’Amico, Ph.D.
鈥淭he arms give the legs a helping hand in locomotor rehabilitation鈥 鈥 Gregory Pearcey, Ph.D. Candidate, M.Sc., Bkin, CSEP-CEP – University of Victoria
鈥淢an-machine interfacing by decoding spinal motor neuron behavior鈥 – Dario Farina, Ph.D. – Imperial College, London
鈥淯se of robots and optimal control theory to study sensorimotor function and dysfunction鈥 – Stephen Scott, Ph.D. – Queen’s University
Thursday, May 16, 2019
Session Five: Emerging Topics
Chair: James Shaughnessy, D.M.D., Kentucky Spinal Cord and Head Injury Research Trust
University of Louisville and University of Kentucky Trainees
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Session Six: Novel Techniques Driving Novel Neuroscience
Chair: Scott R. Whittemore, Ph.D.
鈥淟ight-sheet microscopy in CNS injury and neuroregeneration鈥 – Pantelis Tsoulfas, M.D. – University of Miami
鈥淭he mechanical regulations of neuronal growth and regeneration鈥 – Kristian Franze, Ph.D. – University of Cambridge
鈥3-D Printed neural regeneration devices鈥 – Michael McAlpine, Ph.D. – University of Minnesota
Session Seven: Developmental Plasticity: From Pediatrics to Adults
Chairs: Andrea Behrman, Ph.D. and David Magnuson, Ph.D.
鈥淓arly, intensive leg training to enhance gross motor function in children with perinatal brain injury鈥 – Jaynie Yang, PT, Ph.D. – University of Alberta, Edmonton
鈥淥ptimizing motor recovery for children and adults with cerebral palsy鈥 – Kathleen Friel, Ph.D. – Cornell University Medical College
鈥淣ew advances into the diencephalic control of locomotion鈥 – Patrick Whelan, Ph.D. – University of Calgary
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