, offered through the as part of the Mid-South NSF I-Corps Hub, is an intensive course focused on , which helps innovators and entrepreneurs test their ideas or products in the real world and see if they have what it takes to stick. The regular eight-week program is hybrid and offered in spring and fall, while the new three-session ‘short course’ is offered virtually and in summer.��

“Entrepreneurs and innovators are nimble — they need to move fast to get their ideas from mind to market,” said Jessica Sharon, UofL senior director of innovation and new ventures. “With this new, shorter program, we’re able to offer training and coaching through a more flexible format that helps them move quickly and fits into busy schedules.”��

LaunchIt’s curriculum, taught by experienced and successful entrepreneurs from both the Office of Research and Innovation and UofL College of Business, includes coaching, mentoring and lessons on customer discovery, product validation and other considerations when preparing for market launch. The program is open to anyone in the region working to develop a technology-focused product or company.

UofL piloted the short course in summer 2024. A total of 13 teams participated, including 11 from UofL and one each from Northern Kentucky University and University of Kentucky. Connor Centner, a post-doctoral researcher in the UofL J.B. Speed School of Engineering, used the course to help further a cutting-edge therapeutic ultrasound technology meant to destroy cancer cells and unlock the body’s immune system to fight tumors.

“The LaunchIt Short Course was an incredibly unique experience—it gave me the opportunity to dive into customer discovery and product-market fit with guidance from experienced entrepreneurs who’ve been through it all,” Centner said. “It wasn’t just about learning the basics; it was about gaining real-world experience that offered valuable insight into the market and helped me truly understand customer needs to determine how my idea or product could succeed.”

From the short course, some teams may choose to go on to the more comprehensive eight-week course offered twice a year, or some may choose to focus on additional customer discovery. All participating teams are eligible for microgrants to support customer discovery once they graduate the short course or the full course.

LaunchIt course director, Jamie Rush, said everyone can benefit from entrepreneurial training. With this new short course, the team hopes to expand access to people who may not be able to attend otherwise. For example, the short course is now offered to UofL students in a partnership with the new Bluegrass Biodesign program, where multi-disciplinary teams work to develop innovations that save and improve lives.��

“Whether or not you plan to launch a startup, you’re an entrepreneur and can use LaunchIt tools like customer discovery and market research to focus your research or idea and make it impactful,” Rush said. “We want to equip everyone — students, faculty, staff, entrepreneurs, corporate business leaders — with tools that help them advance not only important new products, but new community projects, business initiatives and more.”��

The next full session of LaunchIt, beginning in spring 2025, is now enrolling through Jan. 24, 2025. More information and registration is available at . The next short course will be offered in summer 2025.��

Suspended in a pediatric therapy harness, the boy’s feet moved across the treadmill. Each foot strike represented new hope for kids living with neurological conditions – to regain motor function, improve trunk control and even take steps on their own.������

That technology, invented by UofL researchers, is helping patients thanks to UofL’s unique suite of programs aimed at moving biomedical research from lab to market as products that can save and improve lives. Now, via a new partnership called the MidSouth Hub, UofL is offering its expertise to researchers across the four-state region of Kentucky, Virginia, Mississippi and Tennessee.����

“Seeing how the technology we’d worked so hard to support could impact that boy’s life was one of the proudest moments of my career,” said Jessica Sharon, senior director of innovation programs and new ventures at UofL. “That’s when I knew we were building something special here at UofL. With the MidSouth Hub, we can expand that impact and ensure even more potentially life-changing technologies make it out of universities and help patients.”��

PROOF OF CONCEPT��

UofL’s focus on innovation begins with the belief that good ideas shouldn’t stay in the lab — they belong out in the world, where they can make a positive impact as new diagnostics, treatments and therapeutics. To that end, the university has spent the past decade aggressively growing its support for biomedical innovation, helping researchers develop, test and refine their ideas before launch.��

UofL secured its first biomedical product innovation grant, the Wallace H. Coulter Translational Partnership, in 2011. Building on that success, UofL landed two more programs a few years later: Kentucky’s first NSF Innovation Corps (I-Corps) site and NIH Research Evaluation and Commercialization Hub (REACH), led by now retired professor, Paula Bates.����

Those were quickly followed by another award, then another, then another, and today, UofL holds a robust suite of programs unique from its peers across the country.�� With each new round of funding UofL forged�� new partnerships that expanded the impact first across the Commonwealth, and now, to the four-state region. The result is the MidSouth Hub, a multi-institution partnership led by Vanderbilt University, with UofL providing its original programming and leading efforts in Kentucky.��

“UofL has developed strategies that can help anyone to create healthcare solutions, whether you are a professor at a large university or a student at a technical college,” said Matt McMahon, Director of the NIH’s SEED (Small business ����ֱ�� and Entrepreneurial Development) Office, which supports REACH. UofL is the only university to succeed in all three rounds of REACH funding.��

“And in the end,” he said, “it’s patients and communities that benefit. We’re very excited to see UofL offer their leadership and expertise in scaling their approach across a broader part of the country.”��

That approach is key to developing technologies like the pediatric therapy harness, which provides partial body weight support as therapists help the kids move their feet over the treadmill. The idea is to slowly and safely turn on muscles and gain control. Designed by researchers Andrea Behrman and Tommy Roussel, that technology has since been licensed and units are in-place or on their way to facilities in Pennsylvania, Texas and New York, as well as Kentucky.��

“I don’t know a university that supports faculty more for innovation and biomedical design than UofL,” said Behrman, a professor of neurological surgery and director of the Kosair for Kids Center for Pediatric NeuroRecovery. “It’s a massive help in moving good ideas down the path, and getting them out where they can actually help patients.”��

THE RIGHT STUFF��

When it comes to good ideas, UofL has plenty to choose from. A Carnegie Research-1 university with a robust academic medical center and affiliated health system, UofL’s clinicians and researchers work to discover, invent, test and implement cutting-edge medical innovations that ultimately are commercialized.����

“This kind of direct impact just isn’t possible without those ingredients,” said Jon Klein, UofL’s interim executive vice president of research and innovation and vice dean for research at its School of Medicine. “That intersection of medicine, research and our suite of innovation programs — that mix is driving positive patient outcomes here and beyond.”��

Those positive outcomes cover a range of potentially devastating diagnoses. Take the�� cancer-fighting technology invented by researchers Geoffrey Clark, Joe Burlison and John Trent, which works by targeting the RAS protein. When mutated, RAS turns into a stuck accelerator pedal, with cells suddenly growing very fast and penetrating other tissue, just like a tumor cell.������

Stopping that process has long been considered a ‘holy grail’ that could shut down at least a third of human tumors. Thanks in part to support from UofL’s innovation programs, that technology is now in development with Qualigen Therapeutics, Inc., a publicly traded California-based biomedical company, and moving down the long pathway to FDA approval.����

“UofL is in a unique position to develop technologies like this because you not only have actual clinicians and cutting-edge research, but programs to assist industry partners to drive the resulting innovations to market,” said Michael Poirier, the company’s Chairman and CEO. “We look forward to continuing work with UofL and to advancing these important clinical technologies with the goal of developing an effective treatment for this unmet need.”��

READY TO LAUNCH��

Over the past decade, UofL’s I-Corps and REACH programs have supported hundreds of innovators, dozens of new products and licensing agreements, millions in follow-on funding and the launch of at least 16 new companies.��

One of those companies is led by School of Medicine researcher Matthew Neal, who participated in UofL’s Economic Development Administration-backed PRePARE program for developing pandemic-related technologies, along with the I-Corps site before going on to the prestigious national NSF program to develop his VR technology for patients with hearing deficiencies.��

Neal’s technology aims to help patients program their hearing aids and test out different models in realistic virtual environments, such as a noisy restaurant, all without leaving the comfort of the clinical setting.��

That led to a startup, Immersive Hearing Technologies, which Neal co-founded with former university entrepreneur-in-residence, Jeff Cummins. Together, they’ve already secured non-dilutive follow-on funding and are on their way to improving the clinical processes behind a widespread problem – hearing loss – affecting one in eight Americans over the age of 12.����

“The innovation programs were invaluable in understanding who our customers are, what they needed and how we might get this technology to market,” Neal said. “It’s no good if an idea like this just sits on a shelf. This is a technology that can help people, and it needs to be out in the world to do that.”����

And that’s the goal, Sharon said.����

“We don’t want good ideas to stay on our campus or any campus,” Sharon said. “With these programs, we’re going to keep growing, keep pushing, to move these innovations from lab to market. And with this new MidSouth Hub, I know we can do that on an even bigger scale.”��

The Mid-South , backed by a four-year grant from the National Institutes of Health, spans a four-state network of Kentucky, Mississippi, Tennessee and Virginia. The hub is led by Vanderbilt University, with UofL leading efforts in Kentucky to transform academic discoveries into real-world products that advance human health and catalyze a medical innovation economy.��

“UofL is a top-tier, Carnegie Research-1 university, and we are proud of our strong track record as a driver of health innovation and entrepreneurship,” said Kevin Gardner, executive vice president for . “We are excited to expand that work with the Mid-South Hub, joining our partner institutions to accelerate technologies and companies that can save and improve lives, creating opportunity here and throughout our region.”

NIH’s REACH program focuses on bringing basic science discoveries to market by providing entrepreneurial training for innovators on how to bring technologies to market; feedback from federal and industry experts; funding to support early-stage product definition studies; and project management support

UofL’s role in the new hub follows years of state leadership, since launching Kentucky’s first REACH program in 2015. The REACH efforts began at UofL and expanded statewide in 2019 through collaboration with KY Innovation, University of Kentucky and Kentucky Commercialization Ventures. Over nearly a decade, Kentucky REACH programs have coached more than 400 innovative faculty, staff and students across Kentucky public institutions and funded 45 technologies, leading to 18 new products and 11 patents filed.

“UofL has provided consistent leadership in driving these innovations from lab to market across the Commonwealth,” said Jessica Sharon, director of innovation programs and lead for the UofL Hub program. “Through this new Hub, we are very excited to work with our regional partner universities to train more innovator teams, helping them learn the product development process and lens.”

REACH is part of UofL’s unique suite of prestigious, grant-backed programs aimed at supporting the translation of research into viable commercial products. UofL is one of only a handful of universities in the country to host each of these innovation-associated programs — and it’s the only one to receive��all��of them.

With the new Mid-South REACH Hub, UofL will expand on this programming by leveraging already strong partnerships with regional institutions. Last year, UofL partnered with Vanderbilt on a $15 million effort backed by the National Science Foundation to launch a new regional hub aimed at accelerating product innovation, entrepreneurship and economic development. The resulting NSF Mid-South��Innovation Corps��(I-Corps) Hub, one of only 10 across the U.S., is part of the operational backbone of the NSF’s , which helps translate academic research for the marketplace while expanding access and inclusion.��

“Diverse perspectives are essential to turn university ideas into lifesaving tools in the hands of doctors,” said Vanderbilt lead, Robert Webster. “So many students and faculty share this vision—to their very core—but lack the business, legal and practical insights they need to get started…��We know what it feels like and what it takes, and we can’t wait to help others unlock the potential of their ideas–and themselves–as innovators and entrepreneurs.”��

NIH will contribute $4 million toward the Hub over four years, with more than $8 million in additional matching funds from partnering universities, state economic development entities and public-private partnerships.��Kentucky matching funds are supported by the state Cabinet for Economic Development’s KY Innovation, UofL and UK. In addition to Vanderbilt and UofL, the other partner institutions are, Jackson State University, George Mason University and UK.

The companies have all been awarded Phase 1 Small Business Innovation Research (SBIR) grants from the National Institutes of Health along with matching funds from the Kentucky Cabinet for Economic Development��to support continued research and development work with UofL.��

The three startups are:��

• Degranin Therapeutics LLC: Degranin Therapeutics, founded by five UofL researchers and led by Kenneth McLeish (School of Medicine), is working to commercialize a UofL research-backed drug for acute respiratory distress syndrome, a rapidly developing, life-threatening lung disease occurring in more than 200,000 hospitalized patients in the U.S. each year. Degranin received more than $300,000 from the SBIR program for development, plus an additional $100,000 in SBIR matching funds from the state.��
• DesiCorp Inc.: is working to develop and commercialize a UofL-born method of freeze-drying blood to extend its shelf-life, which could have , including in the military operations, humanitarian aid or even space travel. The company is led by UofL alum, Brett Janis, and based on technology he developed with researchers Michael Menze () and Jonathan Kopechek (). DesiCorp received nearly $300,000 from the SBIR program, plus nearly $100,000 in additional matching funds from the state. ��
• WickedSheets: is a Louisville-based moisture-wicking bedding startup led by UofL alum, Ali Truttman. WickedSheets is working with UofL researcher Cindy Harnett (J.B. Speed School of Engineering) to develop the Wicked Smart Pad, washable bedding with sensors for the detection and mitigation of moisture events, which could help bedridden patients and home caregivers. WickedSheets received more than $340,000 from the SBIR program, plus nearly $100,000 in additional matching funds from the state.��

“These companies are all working to further UofL research and technology with the potential to save and improve lives,” said Jessica Sharon, director of innovation programs in the university’s . “I’m so proud of what they’ve accomplished, and each one is an excellent example of the strong infrastructure at UofL that supports this kind of innovation and entrepreneurship.”

In addition to being based on UofL research, all three technologies are protected through Office of Research and Innovation’s patenting and licensing team. All three also received coaching and training through the office’s entrepreneurial arm,����and its entrepreneurs-in-residence program, which brings seasoned founders to the university to help guide innovations to market. The program is supported by Amplify Louisville.��

WickedSheets and DesiCorp also received development funding through UofL’s suite of innovation grant programs, which support the translation of research into viable commercial products.��WickedSheets participated in PRePARE, which accelerates development of COVID-19 related technologies, and DesiCorp received funding through UofL’s innovation grants, and NIH REACH programs, which accelerate engineering and biomedical technologies. UofL is one of only a handful of universities in the country to receive each of these, and is��the only one to receive all of them.

KYNETIC is a National Institutes of Health (NIH) funded Research Evaluation and Commercialization Hub (REACH) and part of the national NIH Proof-of-Concept Network. The program offers entrepreneurial education and proof-of-concept/product development grants to accelerate the translation of research innovations into biomedical products by investigators throughout the Commonwealth of Kentucky.�� ��

The goal is to advance the most promising biomedical research innovations — including pharmaceuticals, devices and apps — from the state’s eight public universities and the Kentucky Community & Technical College System (KCTCS).

In this cycle, KYNETIC awarded roughly $40,000 grants to each of the following research teams:

• Christina Ralph-Nearman and Cheri Levinson, University of Louisville
• Melissa Smith and Corey Watson, University of Louisville
• Stuart Williams, Maxwell Boakye and Michael Voor, University of Louisville
• Daniel Boamah, Kimberly Greene and Austin Griffiths, Western Kentucky University
• Jamie Fredericks, Eastern Kentucky University
• Mark Fritz and Guigen Zhang, University of Kentucky��
• Jill Kolesar and Chris Richards, University of Kentucky
• Brittany Levy, University of Kentucky

KYNETIC is led by UofL, the University of Kentucky, the Kentucky Cabinet for Economic Development and Kentucky Commercialization Ventures. Launched in 2019, the KYNETIC program builds on UofL’s strong history of translational research support, which includes a prestigious for turning research into products.

“These programs help to drive UofL research from lab to market – impactful research with the power to improve and even save lives,” said Jessica Sharon, UofL’s director of innovation programs who helps lead KYNETIC. “The UofL projects selected for KYNETIC funding in this cycle embody that goal.”

The pre-application window for KYNETIC’s Cycle 8 is currently open. The deadline is July 18, 2023, by 5 p.m. Pre-applications can be��.

KYNETIC Project Managers are available for consultation before you submit your pre-application and throughout the application process. You can find more information��.

The awards honor “those who have made an impact on health care in our community through their concern for patients, research, innovation, management skills and rising stars in the field,” according to the publication.��

The UofL honorees are:

• Health Entrepreneur: Will Metcalf, associate vice president for research development and strategic partnerships in the . Metcalf leads UofL New Ventures, a team dedicated to furthering research-backed startups, including those in healthcare. He also leads UofL’s innovative collaborations with the Louisville Healthcare CEO Council, a group working to innovate and solve important problems in healthcare.
• Health Equity Champion: Edward Miller with UofL Health and UofL Physicians – OB/GYN & Women’s Health. In addition to caring for high-risk mothers with complicate pregnancies, Miller has a passion to improve health care in underserved neighborhoods and inspire Black youth to pursue health care careers. His leadership helped develop the Pre-Medical Magnet Program and JCPS’ Central High School. The program brings medical professionals into their classroom and brings the high school students into UofL Hospital for a hands-on shadow experience.��
• Health Innovator: Jessica Sharon, director of innovation programs in the Office of Research and Innovation. She leads UofL’s prestigious suite of programs that accelerate translation of research-born innovations to the marketplace, including the university’s new role as part of the NSF Innovation Corps MidSouth Hub.��UofL is one of only a handful of universities in the country to host each of these innovation-associated programs — and it’s the only one to receive��all��of them.��
• Health Manager: Melisa Adkins, CEO of UofL Health’s Mary & Elizabeth Hospital. Since joining UofL Health, two years ago, Adkins has combined her experience as a nurse and administrator to improve access to care in south Louisville. She led the efforts to open a 20-bed medical detox unit, women’s health center, and brought a Brown Cancer Center location to the Mary & Elizabeth hospital campus. She’s also recruited more medical specialists to the area and grew the family medicine practice to ensure residents from the UofL School of Medicine could better experience training in a community medicine environment.��
• Emerging Star (joint award): Mandi Walker, system executive director for the UofL Health Office of Professional Practice, Nursing Research and Nursing ����ֱ��; and Kelly Russell, the office’s director. Walker and Russell provided the oversight for UofL Hospital’s recent designation as a magnet hospital, the gold standard in recognizing professionalism and teamwork in nursing with superiority in patient care. It was a team recognition but could not have happened without these outstanding nursing leaders.

This year’s Health Care Heroes will be profiled in the Feb. 17��edition of Louisville Business First, and will be honored at an in-person event the day before at The Olmsted. You can find more details and register to .

The program provides training and $50,000 to develop new, technology-backed startups. The UofL team, led by School of Medicine research scientist Matthew Neal, completed an intensive, two-month boot camp learning about commercialization, engaging with industry and talking to more than 100 potential customers.

Neal and his collaborators — co-technical leads Pavel Zahorik and Shae Morgan, both in the audiology department — are developing a virtual reality-based technology to help patients test different models and program their hearing aids, without leaving the comfort of the clinical setting.��

With this tool, audiologists could use a VR headset or a wide screen display to demonstrate how specific hearing aid models and settings would perform in different, realistic environments, such as a school, noisy restaurant, grocery store or church. The idea, Neal said, is to help patients find the right fit.

“It’s kind of like test-driving a new car and seeing how it performs in real-world conditions,” Neal said. “We want to help people choose the hearing aid and get it programmed specifically for the specific environments where they have trouble, and with virtual reality technologies, you can do that without leaving your audiologist’s office.”

According to the National Institutes of Health, one in eight Americans over the age of 12 have some degree of hearing loss and about 28.8 million adults could benefit from using hearing aids.

Following the I-Corps national program, the researchers now are developing a working prototype and considering various funding routes to continue research efforts and pursue commercialization of the technology. Their product development efforts are supported by business mentor Tendai Charasika, an Entrepreneur-in-Residence in the UofL Office of Research and Innovation.

The team is also in a research partnership with both the��Heuser��Hearing Institute, a not-for-profit hearing healthcare organization serving Kentuckiana, and Sonova, a hearing aid manufacturer.

“We are proud that our decades-long partnership with the University of Louisville to further the field of audiology with cutting-edge hearing healthcare technology has led to this recognition,” said House CEO Brett Bachmann.��“Congratulations��to Matthew Neal, Pavel Zahorik and Shae Morgan.

Teams must be nominated for the national I-Corps Teams bootcamp, and must first complete UofL’s regional I-Corps site program and , UofL’s product innovation bootcamp. UofL and partners recently received $15 million from the National Science Foundation to launch a new regional��NSF Mid-South��Innovation Corps��(I-Corps) Hub, one of only 10 across the U.S.

Neal’s team also received funding and coaching through UofL’s Pandemic-Related Product Acceleration & Responsive Entrepreneurship Program, or PRePARE, which partners UofL researchers with companies and members of the community to scale up innovative ideas addressing health, economic and societal issues caused by pandemics. The PRePARE program fostered the additional collaboration between UofL and Heuser Hearing Institute.��

“These programs support commercialization of the work being done by our researchers here at UofL,” said Jessica Sharon, UofL’s director of innovation programs. “We’re proud of Matthew and the team at the Heuser Hearing Institute, and their work to accelerate product development of this innovation that addresses unmet needs in the�� market and could help many people.”��

The new , one of only 10 across the U.S., is part of the operational backbone of the NSF’s National Innovation Network, which helps translate academic research for the marketplace. The Hubs are charged with providing experiential entrepreneurship training to researchers across all fields of science and engineering while working to build diverse and inclusive regional innovation ecosystems.

The MidSouth Hub is a collaboration among nine regional research universities, led by Vanderbilt University and including UofL, George Mason University, Jackson State University, Meharry Medical College, Tennessee State University, the University of Kentucky, the University of Tennessee – Knoxville and the University of Virginia. As part of the Hub, UofL will receive $1 million over five years to support focused product development and training.��

“As a top-tier, Carnegie Research-1 university, UofL has a strong track record as a driver of technological innovation and entrepreneurship,” said Kevin Gardner, executive vice president for research and innovation. “We are excited to work with our Mid-South Hub partner institutions to accelerate that work, furthering important and often life-saving technologies, launching new growth-focused companies and creating opportunity here and beyond.”��

UofL’s role in the new hub follows years of leadership as a member of NSF’s I-Corps Site Program. UofL was named an I-Corps Site in 2015, the first in Kentucky, and has since awarded product development training and microgrants to more than 250 innovative faculty, staff and students.

Those awards have supported the creation of at least 16��new companies, eight intellectual property��licensing agreements and more than $8 million in follow-on funding secured to further product development. Several UofL teams also have been selected to participate in the competitive I-Corps National TEAMS program, each receiving $50,000 to further develop technologies that could improve health care through artificial intelligence, extend the shelf-life of donated blood and more.��

“Our goal is to take these brilliant research-backed ideas out of the lab and develop them into full-fledged, market-ready products that can improve the way we live and work,” said Will Metcalf, an associate vice president for research and innovation and a lead for the UofL program. “Participating in the new Mid-South Hub dramatically expands our ability to support the development and growth of scalable companies that bring ideas to life.”����

UofL’s I-Corps programming is led by UofL New Ventures in the , and includes entrepreneurial mentors, prototyping support and , UofL’s eight-week product innovation bootcamp. The office strives to launch and scale innovative companies that can bring technologies to market and solve big problems.

I-Corps is part of UofL’s unique suite of prestigious, grant-backed programs aimed at supporting the translation of research into viable commercial products. UofL is one of only a handful of universities in the country to host each of these innovation-associated programs — and it’s the only one to receive��all��of them.

“These programs have helped support a wide range of technologies and teams, helping them learn the product development process and lens,” said Jessica Sharon, director of innovation programs and a lead on the UofL Hub program. “Through this new Hub, we are very excited to work with our regional partner universities to train more innovators and get research-backed products to market.”

UofL New Ventures, within the , will be dedicated to broad entrepreneurial support, from forging connections with experienced and potential company founders to helping the resulting startups attract funding and market share. The goal is to launch innovative new companies that can spur economic development and move research-backed technologies to market.

“UofL already has a long track record of success in getting its research out into the world as new products, therapies, businesses, educational platforms, creative pieces and other works that can save and improve lives,” said Kevin Gardner, executive vice president for research and innovation. “The creation of this new office ultimately will lead to even greater societal impact of UofL research and the technologies and startups it generates.”

UofL New Ventures will be led by Will Metcalf, associate vice president for research development and strategic partnerships. Its leadership team includes Jessica Sharon, director of innovation programs, and Will Fortune, UofL’s program director for the National Security Innovation Network.

This team has broad and deep expertise, ranging from translational research and commercialization, to corporate innovation and engagement, to launching partnerships that spur regional entrepreneurship.

UofL New Ventures will work closely with the UofL , which is responsible for managing the university’s intellectual property and making decisions about its licensing�� to existing entities or to new startups. Together, the two units will work to connect UofL IP with potential founders.

As part of that work, UofL New Ventures will oversee the university’s Entrepreneurs-in-Residence program, which brings seasoned founders to UofL to help shepherd technologies to market. The office also will also help manage the effort to support regional startup development and success, run in collaboration with the Louisville Healthcare CEO Council.

“We’ve had a lot of success and built momentum with these efforts to spur entrepreneurship and innovation on our campus and beyond,” said Metcalf, who helped launch the LEAP entrepreneurship effort and several successful startups. “With this new office, we are bringing several of our efforts together to accelerate that momentum, creating meaningful impact through translational research, innovation, entrepreneurship and economic development.”

UofL, its innovation and commercialization enterprise and its faculty and researchers already have a strong record of pushing university innovations out into the world. In fiscal year 2020, UofL was awarded 48 new patents and earned $9.4 million from license royalties and other related income, its best year on record and a 30% increase over the year prior. The increased income was propelled by a strong year of deals and startups, with seven new companies launched. Those startups include a new company commercializing a university technology for producing low-calorie sweetener and bio-coal from spent distillers’ grain and one commercializing a tool for��measuring employee engagement.

More recently, UofL has extended that expertise to other universities, helping to bring innovations from across the state of Kentucky to market through efforts such as Kentucky Commercialization Ventures. UofL also has earned from the Association of Public and Land Grant Universities, reflecting its institution-wide commitment��and impact on regional economic growth and economic opportunity.

For more information, visit the UofL New Ventures website .

The program provides training and $50,000 in funding that helps university researchers translate the ideas they develop in the lab into new, technology-backed startups. Participating teams complete an intense, two-month bootcamp learning about commercialization, engaging with industry and talking to potential customers.

Two projects from UofL were chosen to participate in recent bootcamp cohorts:

• BioCaRGOS, short for Capture and Release Gels for Optimized Storage (bioCaRGOS), uses a novel water-based stabilizer to enable storage of sensitive biospecimens like RNA, DNA or proteins at low temperatures for long periods of time, including during transport to remote locations. The project team includes: co-inventors Gautam Gupta and��Rajat Chauhan, both in the J.B. Speed School of Engineering, and business mentor Jeff Cummins, who also is an Entrepreneur-in-Residence with the UofL Office of Research and Innovation.

• ARNA, short for , an artificially intelligent health care robot created to provide round-the-clock patient monitoring and allow nurses to focus more on direct patient care by taking on some of their time-consuming tasks. The project team includes: co-inventors Dan Popa and Sumit Kumar Das, of engineering, and business mentor Mary Tapolsky, of the UofL Forcht Center for Entrepreneurship.

Chauhan, of the BioCaRGOS team, said the experience helped his team find an industry commercialization partner. They currently are seeking partners for an upcoming application NSF Partnerships for Innovation program, which allows NSF-backed projects like his to work with industry on research and development and accelerate the technology’s path to market.

“Vaccine stability (especially for COVID-19) remains a critical challenge and is the critical bottleneck for effective distribution of the state-of-art MRNA based vaccines to current population,” said Chauhan, BioCaRGOS entrepreneurial lead and a postdoctoral research scientist. “Our technology has the potential to advance the delivery of vaccines at room temperature, a feat that cannot be achieved currently.”

Teams must be nominated for the national I-Corps bootcamp, and must first complete a regional . Both the BioCARGOS and ARNA teams completed UofL’s I-Corps site program — part of UofL’s suite of��, that also includes the UofL , NIH and NSF programs. I-Corps at UofL requires successful participation and completion of , UofL’s own 10-week entrepreneurial bootcamp.

“These programs support commercialization of the work being done by our researchers here at UofL,” said Jessica Sharon, UofL’s director of innovation programs. “We’re proud of the ARNA and BioCARGOS teams, and their work to accelerate product development of their innovations to address unmet needs in the market.”��