Coulter Translational Partnership – UofL News Mon, 20 Apr 2026 15:43:07 +0000 en-US hourly 1 UofL Medicine, Engineering teams build custom treadmill for children with spinal cord injuries /section/science-and-tech/uofl-medicine-engineering-teams-build-custom-treadmill-for-children-with-spinal-cord-injuries/ Mon, 28 Oct 2019 18:42:20 +0000 http://www.uoflnews.com/?p=48661 Children with spinal cord injuries have experienced remarkable results in recovery at the University of Louisville and Frazier Rehab Institute through locomotor training, a therapy designed to help them recover the ability to sit, stand and even walk. In locomotor training, the child is suspended over a treadmill and his or her feet are moved by trainers in a stepping motion. This taps into capability of the spinal cord to help the child regain movement and trunk control.

Andrea Behrman, PhD, of the UofL Department of Neurological Surgery and the (KSCIRC), pioneered the use of locomotor training in children at UofL since 2012. Until now, however, Behrman’s team has used treadmills and harnesses designed for adults that have been adapted for children. The oversized equipment is cumbersome for children and working on cut-down adult-sized devices has resulted in unnecessary strain for the trainers and therapists who work with them.

So, Behrman enlisted Tommy Roussel, PhD, of the at UofL, to engineer a treadmill and harness system specifically for young children. Using engineering expertise, user feedback and a patent held by Susan Harkema, PhD, professor of neurosurgery and a pioneer in spinal cord injury research in adults at UofL, a new treadmill was designed from the ground up just for children. 

“It was kind of like putting a kid on an adult bicycle or watching kids play basketball with a 10-foot goal,” Roussel said. “So we have redesigned the system with the same operational capacity, but with kids in mind.”

The new pediatric treadmill has multiple advantages for both children and trainers:

  • Suspension tower is located behind the child on the treadmill so therapists can more easily and directly engage with the child
  • Narrower tread, focusing the child’s steps and bringing trainers closer to the child’s legs and feet
  • Trainers’ seats are more appropriately positioned closer to the child and are adjustable to accommodate trainers of different heights
  • Treadmill tower swivels to allow the child to be hoisted from a wheelchair and onto the treadmill
  • Smaller, more adaptable harness that is more comfortable and easier to adjust to the child’s changing capability

“The treadmill is a tool for us, but we want it to be a smart tool. By making it better, we are going to do our jobs better and the child is going to participate better,” Behrman said. “We changed it to make the child more accessible to the trainer with good body posture and position for all this repetitive activity.”

Thanks to funding and support from the , the team was able to develop the initial prototype. Behrman and Roussel then collaborated with other specialized manufacturers, further refining the treadmill and harnesses. Once they had a customized treadmill, the team worked to commercialize the device and harness system to make it available to therapists in other centers.

“We starting thinking, ‘How can we make it better?’” Roussel said. “If we are going to move to manufacturing this, how can we make it more modular and with fewer parts that need to be assembled? That’s where the magic and the fun happened.”

The treadmill design was licensed to and units are in place or on their way to facilities in Pittsburgh, Houston and New York, as well as in Louisville at Frazier Rehab Institute.

“In the last several years, we have been able to achieve things that have not historically happened in terms of rehabilitation outcomes for these children,” Behrman said. “Children once unable to sit on their own, for example, can now do so due to locomotor training. Such improvements open up other possibilities to play and engage, and help a child get back on the developmental track. This new treadmill system gives physical therapists and trainers a device that is state-of-the-art in design and utility and revolutionizes the way we deliver locomotor training specifically for children.”

Check out video of the new treadmill system:

 

Donors and developers include: Christopher and Dana Reeve Foundation, Kosair Charitie, WHAS Crusade for Children, Independent Pilots Association Foundation, Ty Adams, Jena Allen, Laura Argetsinger, Andrea Behrman, Yangsheng Chen, Ran Cheng, Susan J. Harkema, Dena Howland, Winston Rauch, Tommy Roussel, Shelley Trimble, Winston Industries, Haffendorfer Machine Inc., Tuff Tread Treadmills, Rich and Norrie Oelkers and the Bonita Bay Tennis Club, Goose Kearse, Rachel Marsilia, MacKenzie Roberts and Misty Mountain Threadworks.

]]>
Kidney project is first to get funding from ‘trifecta’ /post/uofltoday/kidney-project-is-first-to-get-funding-from-trifecta/ /post/uofltoday/kidney-project-is-first-to-get-funding-from-trifecta/#respond Thu, 12 Oct 2017 14:34:01 +0000 http://uoflnews.com/?p=38774 It’s the first University of Louisville project to receive money from three major translational research funding sources, and it could change the way doctors treat kidney transplant patients. UofL bioengineering professor Ayman El-Baz began looking for a non-invasive, less expensive way to detect signs of renal rejection in 2004 when his cousin suffered kidney failure and needed a transplant. El-Baz and Drs. Amy Dwyer and Garth Beache in the UofL School of Medicine worked together to develop RenalCAD, which uses an MRI instead of a biopsy to find signs of renal rejection.

“I like to work in science that can improve health care, especially if the patient is a relative.” El-Baz said.

The project has now been funded by the Coulter Translational Partnership, NSF I-Corps and NSF AWARE:ACCESS, three funding programs aimed to get entrepreneurs and their inventions to the marketplace more quickly and successfully. The group has applied for patent protection and is collaborating with the University of Michigan on a clinical study. Louisville and Michigan are two of just 16 schools in the U.S. to receive funding from the Coulter Foundation.

“We would not have been able to do this without the Coulter funding ($223,000),” El-Baz said.

The money from I-Corps and AWARE:ACCESS has gone to support Isaac Gebru, a UofL Speed School of Engineering graduate who worked with El-Baz and has created a start-up company to commercialize and market the technology. Last year, I-Corps paid for Gebru to complete a UofL Foundation-sponsored training course for upstart businesses called LaunchIt while the AWARE:ACCESS program helps minority entrepreneurs, like Gebru, write more competitive grant proposals and hone their customer relations skills.

“I think this kidney project demonstrates the clear and distinct value of each of these three funding mechanisms,” said Rob Keynton, director of Research Initiatives in the Office of the Executive Vice President for Research and lead investigator of the three awards. “Together, the awards help UofL faculty and students figure out their potential customer base, secure funding and get their innovations to the marketplace.”

]]>
/post/uofltoday/kidney-project-is-first-to-get-funding-from-trifecta/feed/ 0