The two UofL startups, BioProducts LLC and OrgVitals, will be formally recognized in a February live event. To be eligible, startups must be based in Kentucky, have been founded five or fewer years ago and have total raised capital of less than $25 million.

BioProducts is built around UofL-patented technology that gives new life to local distillery organic-based byproducts, for example, as a low-calorie sugar substitute and as specialized activated carbon suitable for a number of high-performance applications, particularly lithium-ion batteries. 

The technology was invented by Jagannadh Satyavolu, of the UofL Conn Center for Renewable Energy Research, in collaboration with Michael Nantz and his team in the UofL chemistry department, and recently took the top spot at the Distillers Grains Reverse Pitch competition.

OrgVitals, which grew out of Unitonomy studio, is a startup leveraging UofL-born intellectual property for employee engagement data and analysis — used for predictive modeling to create healthier places to work. 

That technology was invented by Brad Shuck, an organizational culture and applied behavioral economics researcher in the UofL College of ����ֱ�� and Human Development (CEHD). The , and the first to be supported by the UofL Office of Research and Innovation’s entrepreneurs in residence program, which brings in seasoned founders to help guide the university’s research-backed technologies to market.

UofL supports entrepreneurs through its UofL New Ventures office, which works to launch and grow startups built around . Aside from the entrepreneurs in residence program, the office also supports startups through LaunchIt, a 10-week entrepreneurship and innovation bootcamp, and through a prestigious suite of grant programs aimed at translating university research into products.

“We’re so proud of these UofL startups and the work they’re doing to further innovations that improve the way we work and live,” said Will Metcalf, an associate vice president for research and innovation who leads UofL New Ventures. “This recognition is proof-positive of that, and I can’t wait to see what they accomplish.”

This project will pilot a commercially viable process using previous research to convert soybean hull biomass into a low-calorie, diabetic-friendly sugar substitute while simultaneously extracting micro and nanoscale fibers to be used for lightweight fiber composites and thermoplastic packaging products via 3D printing.

“Agriculture and agricultural processing are keys to economic development and employment in the U.S. Xylose separation and use of soy hull fibers for natural fiber composites are potent opportunities for addressing worldwide farming economics, nutrition issues and material needs from a renewable source,” said Mahendra Sunkara, director of the Conn Center. “In conjunction with BioProducts LLC, the Conn Center expects the development of a pilot-scale operation in the next two years.”

The U.S. has world-scale processing facilities to convert grain and its byproducts to various industrial and food products, including alcohols and spirits, dietary fibers, industrial proteins and others. Both agriculture and agricultural processing generate significant amounts of residual biomass, including 8 million tons per year of soy hulls from soybeans.

The UofL project will utilize these soy hulls to produce xylose, a natural and low-calorie sugar, using a patented process developed by UofL and licensed by , based in Louisville. After xylose extraction, the residual fiber, which is about 80% of the starting biomass, has a modified fiber structure that can be used as a natural fiber in composites for 3-D printing applications.

These natural fiber composites also have potential uses in the automotive, civil engineering, military and aerospace industries, which rely on petroleum-based fiberglass and expensive carbon fiber composites to reduce weight and maintain assembly strength over all-metal constructions. The Conn Center project pursues the development of a stable and efficient method to process the hemicellulose-removed biomass from soybeans into lightweight natural fiber composites.

The food-grade sugar xylose from soy hulls also has high value industrial applications. This sugar can be used to produce cyclopentadiene, a key ingredient in cyclic olefin copolymer (COC), an amorphous thermoplastic used in polyolefin “shrink films” for medical, food safe and industrial packaging. This COC market, which currently depends on petroleum as the source, was valued at $14.9 billion in 2017.

The new USB grant will fund pilot phase development of innovations resulting from previous research at UofL, including 3-D printing using soy hull-polymer composite filaments, , and additive manufacturing prospects, as well as a patent application on polymer composite feedstock production. That work initially was funded by USB in 2019.

The major challenge of utilizing soy hulls to produce sugars and fibers is to create efficient, economical and achievable technology at a commercial scale. Meeting these three criteria elevates the value of this biomass. Currently, one limited outlet for soy hulls is as animal feed. Processing the hulls for a high value product such as xylose could make growing soy more profitable for farmers.

The research team is led by theme leader for at the Conn Center for Renewable Energy Research, and mechanical engineering professor in the UofL . Satyavolu and Kate recruited several graduate students and postdoctoral scholars for the two-year project, “An integrated approach to utilize soy hulls in modified fiber composites for 3-D printing applications and produce xylose as a value-added product.”

In the pilot phase, the team will pursue process optimization and design to meet the demands of a commercially viable process. This includes large volume production of xylose and composite filament samples for evaluation by commercial partners in the food and 3-D printing industries.